INEBIR publishes article in the prestigious scientific journal HUMAN REPRODUCTION refuting the suitability of a novel test that still needs refinement for clinical use. Furthermore, it proposes the technique used at INEBIR, which allows for the diagnosis of 100% of the genetic causes of miscarriage, compared to the 80% that the cfDNA test is able to diagnose.
This study, developed by Doctors Ana Teresa Marcos and José Manuel Navarro Pando, was framed within the Chair of Human Reproduction and Genetics of the Institute for the Study of the Biology of Human Reproduction (INEBIR), the European University of the Atlantic (UNEATLANTICO) and the Ibero-American University Foundation (FUNIBER).
INEBIR It warns that the proposed cfDNA technique is not yet suitable for clinical application, as it has an estimated diagnostic error rate of 28% for chromosomal causes of miscarriage. Additionally, INEBIR proposes the method used in our clinic (QF-PCR, karyotyping, and microarrays, or CMA), which is capable of detecting 100% of chromosomal causes of miscarriage, resulting in better decision-making and improved treatment outcomes for the patient.